产品货号:
Z24444
中文名称:
PPP3CA抗体
英文名称:
Anti-PPP3CA Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-PPP3CA Antibody |
指标别名 | Calcineurin A alpha,CALN,CALNA,CALNA1,CAM PRP catalytic subunit,CCN1,CNA,CNA1,PPP2B,PPP3CA |
克隆性 | Polyclonal |
检验物种 | human,rat |
应用范围 | WB,ICC/IF,FCM(Intracellular),Direct ELISA |
基因名称 | PPP3CA |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | E.coli-derived human PPP3CA recombinant protein (Position:E3-D511). |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Calcineurin A is also known as PPP3CA.It is mapped to 4q24.Semsarian et al.(1999) and Musaro et al.(1999) independently showed that IGF1stimulates skeletal muscle hypertrophy and a switch to glycolytic metabolism by activating calcineurin A and inducing the nuclear translocation of transcription factor NFATC1.Semsarian et al.(1999) found that hypertrophy was suppressed by the calcineurin inhibitors cyclosporin A or FK506,but not by inhibitors of the MAP kinase or phosphatidylinositol-3-OH kinase pathways.Musaro et al.(1999) showed that expression of a dominant-negative calcineurin mutant also repressed myocyte differentiation and hypertrophy.Musaro et al.(1999) demonstrated that either IGF1 or activated calcineurin induces expression of transcription factor GATA2,which accumulates in a subset of myocyte nuclei,where it associates with calcineurin and a specific dephosphorylated isoform of NFATC1. |
Uniprot ID | Q08209 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for ICC. |
基因名全称 | protein phosphatase 3 catalytic subunit alpha |
蛋白名全称 | Protein phosphatase 3 catalytic subunit alpha |
推荐稀释比 | Western blot (WB) 1:500~2000 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50~400 Flow Cytometry(Intracellular) 1~3μg/1×106 cells Direct ELISA 1:100~1000 |
Gene ID | 5530 |
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